French researchers from the Imagine Institute of Genetic Diseases in Paris wanted to know if it was possible to predict which children were at risk of developing this complication.
Fortunately, children are little affected by severe forms of Covid. Nevertheless, the disease induces in a small part of them a pediatric multisystemic inflammatory syndrome (PIMS or MISC) which leads, in some cases, to a myocarditis liable to require them to be transferred to intensive care. Myocarditis is an inflammation of the heart muscle that occurs when cells of the immune system migrate into it abnormally and prevent it from functioning properly.
French researchers from the Institute of Genetic Diseases Imagine in Paris wanted to know if it was possible to predict which children were at risk of developing this complication, which appears 3 to 6 weeks after infection with Sars-CoV-2. Frédéric Rieux-Laucat and Mickaël Ménager, both research directors, studied a cohort of children hospitalized for PIMS during the first wave of Covid, in the spring of 2020. Among 30 children, 21 presented with myocarditis requiring